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"The most important thing, I think, is to have led people to have confidence in themselves, to understand that at last they can sit down and write about their development, write about their happiness and say what they want. And at the same time, to feel what the price is for happiness".
Thomas SANKARA

Santé mentale
Grants to optimise mental health outcomes

Deadline: 09-dec-2021

Name of donor : National Institutes of Health

Grant size : more than a million dollars

Category: Grant

Reference URL : Click here


The National Institutes of Health (NIH) has announced requests for research into the effectiveness and implementation of post-acute interventions to optimise long-term mental health outcomes.


This FOA seeks research applications for effectiveness and implementation science on the post-acute (long-term or chronic) management of mental health problems. This funding opportunity aims to advance the development of new and innovative implementation research to improve the availability and accessibility of post-acute services in low- and middle-income countries (LMICs) and low-resource settings.

This FOA aims to support developmental research projects to evaluate the effectiveness and implementation of therapeutic interventions and services for the management of the post-acute phase of mental health problems affecting children, young people, adults and older people in LMICs. All applications are also expected to generate new information about the structure of the health system and the changes that may be needed to facilitate the dissemination (scale-up and sustainability) of these interventions. Pilot clinical trial studies can assess these facilitators and barriers, while non-clinical trial studies can derive them from secondary data. The potential for reciprocal learning will be considered an added value.

Examples of relevant research topics include, but are not limited to:

  • Designing and testing the feasibility and acceptability of innovative implementation studies of evidence-based ambulatory or community-based pharmacological and psychosocial interventions for post-acute care of common mental disorders or severe mental illness.
  • The role of interventions to address the social determinants of health (including, but not limited to, housing, healthy eating, water, education and employment) as a component of psychosocial interventions for post-acute care
  • Identification of underlying targets/mechanisms that may help to understand causal pathways between post-acute service use and mental health functioning.
  • Planning and pilot testing of evidence-based efficacy, effectiveness and implementation studies of pharmacological and/or psychosocial interventions for adults or children in humanitarian situations.
  • Evaluating the availability and testing the use of routinely collected data within healthcare networks/ESDs to examine population-level strategies for surveillance, incentivising engagement (p. care.
  • The development and testing of innovative strategies or interventions to initiate preventive interventions in children and young people being treated for "intermediate conditions" (e.g. substance use disorders, suicidality, depression).
  • Surveys to study adaptations to the successful implementation of effective interventions for sustained post-acute care and reintegration community people with common mental disorders in LMIC environments, including assessing feasibility and acceptability.
  • Exploring technology-assisted self-monitoring or passive monitoring to detect clinical deterioration or problematic adherence combined with prompts for self-management strategies or more intensive services (e.g. via a patient-clinician/provider interface or portal) ;
  • The development and testing of evidence-based transition planning strategies to facilitate community reintegration, promote continuity of care and prevent rehospitalisation after residential or institutional treatment.
  • Pilot studies to maximise coordination, partnerships and effective communication between inpatient and outpatient care systems on surveillance, interventions and post-acute services.

Information on financing

  • The National Institute of Mental Health (NIMH) intends to commit 2,500,000 $ in the financial year 2022 to fund up to 7 awards.
  • Direct costs are limited to 450,000 $ over the period of the R34 project, with a maximum of 225,000 $ in direct costs authorised in a single year.
  • The total duration of the project for an application submitted in response to this funding may not exceed 3 years.

Eligibility criteria

  • Higher education establishments
    • Public/state-controlled higher education institutions
    • Private higher education establishments
  • The following types of higher education institutions are still encouraged to apply for NIH support as public or private higher education institutions:
    • Institutions serving Hispanics
    • Historically Black Colleges and Universities (HBCU)
    • Tribally controlled colleges and universities (TCCU)
    • Institutions serving Alaska Natives and Native Hawaiians
    • Asian American Pacific Islander Serving Institutions (AANAPISIs)
  • Non-profit organisations other than higher education establishments
    • Not-for-profit organisations with IRS 501(c)(3) status (other than higher education establishments)
    • Non-profit organisations without IRS 501(c)(3) status (other than higher education establishments)
  • Profit-making organisations
    • Small businesses
    • For-profit organisations (other than small businesses)
  • Local government
    • State governments
    • County governments
    • City or cantonal governments
    • Special district governments
    • Indian/Amerindian tribal governments (federally recognised)
    • Indian/Amerindian tribal governments (other than those recognised by the federal government)
  • Federal Government
    • Eligible federal government organizations
    • Territory or possession of the United States
  • Other
    • Independent school districts
    • Public housing boards/Indian housing boards
    • Native American tribal organizations (other than federally recognized tribal governments)
    • Faith-based or community organisations
    • Regional organisations
    • Non-domestic (non-US) entities (foreign institutions)
  • Foreign institutions
    • Non-national (non-US) entities (foreign institutions) may apply.
    • Non-national (non-US) components of US organisations are eligible.
    • Foreign components, as defined in the NIH grant policy statement, are permitted.

Eligible individuals

  • Anyone with the skills, knowledge and resources to carry out the proposed research as a Programme Director(s)/ Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organisation to develop an application for support. People from under-represented racial and ethnic groups and people with disabilities are always encouraged to apply for NIH support.
  • For institutions/organisations proposing more than one PD/IP, please refer to the policy on multiple programme directors/principal investigators and submission details in the Principal Person Profile (developed) component of the SF424 Application Guide (R&R).
  • Applications proposing a single PD/PI must have a principal academic appointment at a PRFI institution. Research projects must be conducted in an LMIC in which the single PD/PI has a principal academic appointment.
  • Applicants proposing IPMs must have at least one PI/PD who has a principal academic appointment at a PRFI institution. Research projects must be carried out in a PRFI in which at least one PD/PI has a principal academic appointment.
  • LMICs are defined according to the World Bank's designations of low- and middle-income countries (LMICs) for the 2022 financial year

For more information, please visit Grants.gov .

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